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CPLC Seminar - Dr. Ting Lu on Friday, October 18, 2019

10/15/2019 11:47:25 AM


Bottom-up Assembly of Microbial Communities: Modeling, Analysis and Engineering

Microbial communities play profound roles in the environment, agriculture and human health. To exploit their potential for applications, a fundamental prerequisite is to decipher the basic rules of community organization in space and time. We aim to address the challenge using a bottom-up approach that integrates experimental synthetic biology with biophysical modeling. Recently, we developed a computational prototype that enables mechanistic simulation of microbial communities. We also explored how the mode of cellular social interaction and the spatial scale of interaction contribute to microbial assemblages using experimental ecosystems. With engineered cellular interactions, we further demonstrated the utility of synthetic ecosystems for metabolic engineering purposes. Our studies provide insights into the assembly of natural communities and illustrate the potential of synthetic consortia for practical purposes.        




Chicago Tribune (Feb. 3) -- To gauge the performance of Illinois universities in facilitating start-ups, the Illinois Science & Technology Coalition conducted its first University Entrepreneurship Survey, which examines the role of educational institutions in launching new ventures by supporting research, technology transfer and entrepreneurship centers. The U. of I. leads institutions outside Chicago with 54 start-ups in the past four years; 48 of which are currently active and making significant contributions.